2.  

Xie, X., Cui, Q., Jiang, T., Zhao, Z., Liu, Z., Liu, J., Yao, Q., Wang, Y., Dang, E., Wang, G., Xiao, L., and Wang, N. (2024) A critical role of the endothelial S-phase kinase-associated protein 2/phosphatase and tensin homologue axis in angiogenesis and psoriasis. Br J Dermatol190, 244-257  

3.  

Wang, T., Song, D., Li, X., Luo, Y., Yang, D., Liu, X., Kong, X., Xing, Y., Bi, S., Zhang, Y., Hu, T., Zhang, Y., Dai, S., Shao, Z., Chen, D., Hou, J., Ballestar, E., Cai, J., Zheng, F., and Yang, J. Y. (2024) MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus. Cell Commun Signal22, 220  

4.  

Ruan, H., Li, X., Zhou, L., Zheng, Z., Hua, R., Wang, X., Wang, Y., Fan, Y., Guo, S., Wang, L., Ur Rahman, S., Wang, Z., Wei, Y., Yu, S., Zhang, R., Cheng, Q., Sheng, J., Li, X., Liu, X., Yuan, R., Zhang, X., Chen, L., Xu, G., Guan, Y., Nie, J., Qin, H., and Zheng, F. (2024) Melatonin decreases GSDME mediated mesothelial cell pyroptosis and prevents peritoneal fibrosis and ultrafiltration failure. Sci China Life Sci67, 360-378  

5.  

Lin, Z. Q., Yao, Y., Zhang, Y. F., Zhang, X. Y., and Guan, Y. F. (2024) Role of prostaglandin E(2) and its receptors in chronic liver disease. Sheng Li Xue Bao76, 329-340  

6.  

Ferrete-Bonastre, A. G., Martinez-Gallo, M., Morante-Palacios, O., Calvillo, C. L., Calafell-Segura, J., Rodriguez-Ubreva, J., Esteller, M., Cortes-Hernandez, J., and Ballestar, E. (2024) Disease activity drives divergent epigenetic and transcriptomic reprogramming of monocyte subpopulations in systemic lupus erythematosus. Ann Rheum Dis  

7.  

Cui, Q., Jiang, T., Xie, X., Wang, H., Qian, L., Cheng, Y., Li, Q., Lu, T., Yao, Q., Liu, J., Lai, B., Chen, C., Xiao, L., and Wang, N. (2024) S-nitrosylation attenuates pregnane X receptor hyperactivity and acetaminophen-induced liver injury. JCI Insight9  

8.  

Zhou, Y., Gu, T., Hu, S., Luo, Z., Huang, L., Yu, C., Wang, J., Liu, B., Zhang, X., and Guan, Y. (2023) Liver HMGCS2 is critical in the maintenance of liver lipid homeostasis during fasting. Genes Dis10, 694-697  

9.  

Zhou, Y., Gu, T., Hu, S., Luo, Z., Huang, L., Yu, C., Wang, J., Liu, B., Zhang, X., and Guan, Y. (2023) Liver HMGCS2 is critical in the maintenance of liver lipid homeostasis during fasting. Genes Dis10, 694-697  

10.  

Wang, G. Y., Zhang, X. Y., Wang, C. J., and Guan, Y. F. (2023) Emerging novel targets for nonalcoholic fatty liver disease treatment: Evidence from recent basic studies. World J Gastroenterol29, 75-95  

11.  

Shen, B., Ma, C., Wu, G., Liu, H., Chen, L., and Yang, G. (2023) Effects of exercise on circadian rhythms in humans. Front Pharmacol14, 1282357  

12.  

Ming, W. H., Luan, Z. L., Yao, Y., Liu, H. C., Hu, S. Y., Du, C. X., Zhang, C., Zhao, Y. H., Huang, Y. Z., Sun, X. W., Qiao, R. F., Xu, H., Guan, Y. F., and Zhang, X. Y. (2023) Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/beta-catenin signaling. Acta Pharmacol Sin44, 2075-2090  

13.  

Marin-Bejar, O., Romero-Moya, D., Rodriguez-Ubreva, J., Distefano, M., Lessi, F., Aretini, P., Liquori, A., Castano, J., Kozyra, E., Kotmayer, L., Bueno, C., Cervera, J., Rodriguez-Gallego, J. C., Nomdedeu, J. F., Murillo-Sanjuan, L., De Heredia, C. D., Perez-Martinez, A., Lopez-Cadenas, F., Martinez-Laperche, C., Dorado-Herrero, N., Marco, F. M., Prosper, F., Menendez, P., Valcarcel, D., Ballestar, E., Bodor, C., Bigas, A., Catala, A., Wlodarski, M. W., and Giorgetti, A. (2023) Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency. Haematologica108, 2551-2557  

14.  

Liu, Z., Zhang, J., Li, S., Wang, H., Ren, B., Li, J., Bao, Z., Liu, J., Guo, M., Yang, G., and Chen, L. (2023) Circadian control of ConA-induced acute liver injury and inflammatory response via Bmal1 regulation of Junb. JHEP Rep5, 100856  

15.  

Liu, Z., Bao, Z., Yu, B., Chen, L., and Yang, G. (2023) Pemetrexed ameliorates Con A-induced hepatic injury by restricting M1 macrophage activation. Int Immunopharmacol125, 111158  

16  

Liu, C., Li, S., Ji, S., Zhang, J., Zheng, F., Guan, Y., Yang, G., and Chen, L. (2023) Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis. Biochim Biophys Acta Mol Basis Dis1869, 166572  

17.  

Du, C., Xu, H., Cao, C., Cao, J., Zhang, Y., Zhang, C., Qiao, R., Ming, W., Li, Y., Ren, H., Cui, X., Luan, Z., Guan, Y., and Zhang, X. (2023) Neutral amino acid transporter SLC38A2 protects renal medulla from hyperosmolarity-induced ferroptosis. Elife12  

18.  

Cao, R., Su, W., Sheng, J., Guo, Y., Su, J., Zhang, C., Wang, H., Tang, Y., Chen, L., Qiao, R., Chen, X., Huang, X., Zhou, Y., Zhu, L., Bai, Z., Zhang, X., Gustafsson, J. A., Wan, Q., Lan, H. Y., and Guan, Y. (2023) Estrogen receptor beta attenuates renal fibrosis by suppressing the transcriptional activity of Smad3. Biochim Biophys Acta Mol Basis Dis1869, 166755  

19.  

Zhou, Y., Zhang, H., Yao, Y., Zhang, X., Guan, Y., and Zheng, F. (2022) CD4(+) T cell activation and inflammation in NASH-related fibrosis. Front Immunol13, 967410  

20  

Yao, Q., Liu, J., Cui, Q., Jiang, T., Xie, X., Du, X., Zhao, Z., Lai, B., Xiao, L., and Wang, N. (2022) CCN1/Integrin alpha(5)beta(1) Instigates Free Fatty Acid-Induced Hepatocyte Lipid Accumulation and Pyroptosis through NLRP3 Inflammasome Activation. Nutrients14  

21.  

Xu, H., Fang, B., Bao, C., Mao, X., Zhu, C., Ye, L., Liu, Q., Li, Y., Du, C., Qi, H., Zhang, X., and Guan, Y. (2022) The Prostaglandin E2 Receptor EP4 Promotes Vascular Neointimal Hyperplasia through Translational Control of Tenascin C via the cAPM/PKA/mTORC1/rpS6 Pathway. Cells11  

22.  

Xiao, L., and Wang, N. (2022) PPAR-delta: A key nuclear receptor in vascular function and remodeling. J Mol Cell Cardiol169, 1-9  

23.  

Xiao, F., Rui, K., Shi, X., Wu, H., Cai, X., Lui, K. O., Lu, Q., Ballestar, E., Tian, J., Zou, H., and Lu, L. (2022) Epigenetic regulation of B cells and its role in autoimmune pathogenesis. Cell Mol Immunol19, 1215-1234  

24  

Su, W., Wu, S., Yang, Y., Guo, Y., Zhang, H., Su, J., Chen, L., Mao, Z., Lan, R., Cao, R., Wang, C., Xu, H., Zhang, C., Li, S., Gao, M., Chen, X., Zheng, Z., Wang, B., Liu, Y., Liu, Z., Wang, Z., Liu, B., Fan, X., Zhang, X., and Guan, Y. (2022) Phosphorylation of 17beta-hydroxysteroid dehydrogenase 13 at serine 33 attenuates nonalcoholic fatty liver disease in mice. Nat Commun13, 6577  

25  

Rodriguez-Ubreva, J., Arutyunyan, A., Bonder, M. J., Del Pino-Molina, L., Clark, S. J., de la Calle-Fabregat, C., Garcia-Alonso, L., Handfield, L. F., Ciudad, L., Andres-Leon, E., Krueger, F., Catala-Moll, F., Rodriguez-Cortez, V. C., Polanski, K., Mamanova, L., van Dongen, S., Kiselev, V. Y., Martinez-Saavedra, M. T., Heyn, H., Martin, J., Warnatz, K., Lopez-Granados, E., Rodriguez-Gallego, C., Stegle, O., Kelsey, G., Vento-Tormo, R., and Ballestar, E. (2022) Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses. Nat Commun13, 1779  

26.  

Morante-Palacios, O., Godoy-Tena, G., Calafell-Segura, J., Ciudad, L., Martinez-Caceres, E. M., Sardina, J. L., and Ballestar, E. (2022) Vitamin C enhances NF-kappaB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells. Nucleic Acids Res50, 10981-10994  

27  

Martins-Ferreira, R., Leal, B., Chaves, J., Ciudad, L., Samoes, R., Martins da Silva, A., Pinho Costa, P., and Ballestar, E. (2022) Circulating cell-free DNA methylation mirrors alterations in cerebral patterns in epilepsy. Clin Epigenetics14, 188  

28.  

Luan, Z. L., Zhang, C., Ming, W. H., Huang, Y. Z., Guan, Y. F., and Zhang, X. Y. (2022) Nuclear receptors in renal health and disease. EBioMedicine76, 103855  

29.  

Liu, Y. H., Liu, Y., Zhang, X., Fang, L., Zhao, B. L., and Wang, N. P. (2022) Activation of the endocannabinoid system mediates cardiac hypertrophy induced by rosiglitazone. Acta Pharmacol Sin43, 2302-2312  

30.  

Liu, J., Yao, Q., Xie, X., Cui, Q., Jiang, T., Zhao, Z., Du, X., Lai, B., Xiao, L., and Wang, N. (2022) Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARgamma-Dependent Mechanism. Nutrients14  

31.  

Li, Y., Cao, R., Gu, T., Cao, C., Chen, T., Guan, Y., and Zhang, X. (2022) PPARbeta/delta Augments IL-1beta-Induced COX-2 Expression and PGE2 Biosynthesis in Human Mesangial Cells via the Activation of SIRT1. Metabolites12  

32.  

Godoy-Tena, G., Barmada, A., Morante-Palacios, O., de la Calle-Fabregat, C., Martins-Ferreira, R., Ferrete-Bonastre, A. G., Ciudad, L., Ruiz-Sanmartin, A., Martinez-Gallo, M., Ferrer, R., Ruiz-Rodriguez, J. C., Rodriguez-Ubreva, J., Vento-Tormo, R., and Ballestar, E. (2022) Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of inflammatory cytokines. Genome Med14, 134  

33.  

Godoy-Tena, G., and Ballestar, E. (2022) Epigenetics of Dendritic Cells in Tumor Immunology. Cancers (Basel)14  

34.  

Ferrete-Bonastre, A. G., Cortes-Hernandez, J., and Ballestar, E. (2022) What can we learn from DNA methylation studies in lupus? Clin Immunol234, 108920  

35.  

de la Calle-Fabregat, C., Rodriguez-Ubreva, J., Ciudad, L., Ramirez, J., Celis, R., Azuaga, A. B., Cuervo, A., Graell, E., Perez-Garcia, C., Diaz-Torne, C., Salvador, G., Gomez-Puerta, J. A., Haro, I., Sanmarti, R., Canete, J. D., and Ballestar, E. (2022) The synovial and blood monocyte DNA methylomes mirror prognosis, evolution, and treatment in early arthritis. JCI Insight7  

36.  

de la Calle-Fabregat, C., Rodriguez-Ubreva, J., Canete, J. D., and Ballestar, E. (2022) Designing Studies for Epigenetic Biomarker Development in Autoimmune Rheumatic Diseases. Rheumatol Immunol Res3, 103-110  

37.  

Zhang, H. B., Su, W., Xu, H., Zhang, X. Y., and Guan, Y. F. (2021) HSD17B13: A Potential Therapeutic Target for NAFLD. Front Mol Biosci8, 824776  

38  

Yu, H., Jiang, S., Huang, Y., Li, X., Wang, X., Chen, L., and Chen, J. (2021) Characterizing Brain Signals for Epileptic Pre-ictal Signal Classification. AMIA Annu Symp Proc2021, 1215-1224  

39.  

Xu, H., Wang, S. L., Bao, C. Z., Ye, L., Guan, Y. F., and Zhang, X. Y. (2021) [Overexpression of human EP4 receptor in vascular smooth muscle cells attenuates angiotensin II-induced hypertension in mice]. Sheng Li Xue Bao73, 597-605  

40.  

Luan, Z. L., Wei, Y. Y., Wang, Y. C., Ming, W. H., Zhang, H. B., Wang, B., Cui, X. H., Li, Y. Y., Guan, Y. F., and Zhang, X. Y. (2021) Farnesoid X receptor (FXR) inhibits coagulation process via inducing hepatic antithrombin III expression in mice. Sheng Li Xue Bao73, 795-804  

41.  

Luan, Z. L., Ming, W. H., Sun, X. W., Zhang, C., Zhou, Y., Zheng, F., Yang, Y. L., Guan, Y. F., and Zhang, X. Y. (2021) A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury. Am J Physiol Renal Physiol321, F617-F628  

42.  

Li, S., Su, W., Zhang, X. Y., and Guan, Y. F. (2021) [Arachidonic acid metabolism in liver glucose and lipid homeostasis]. Sheng Li Xue Bao73, 657-664